Chromatography Solutions



Chromatography applications are run daily in laboratories worldwide and many of these applications can be reused by other laboratories working in the same area. Method developers like to share their results to accelerate development and to ensure that their work is not duplicated; analysts also require a quick way to find chromatography methods for the compounds they are analyzing.


To effectively compare and evaluate applications, the following data must be stored and also be easily accessible:

  • Results such as peak name and peak resolution
  • Information about the instrument used, such as detector and pump type
  • Column details, such as manufacturer, length, internal diameter, packing material, and particle size
  • Method details, such as flow rate, gradient table, injection volume, column temperature, and detector wavelength
  • Raw data to allow visualization of the chromatogram

A chromatography application

A chromatography application is the analysis and determination of
certain properties of a sample, such as the amount of a compound of


interest. The process consists of the following details: 

  • Instrument used for analysis
  • Instrument settings including flow, injection volume, and detector
  • Raw data including chromatograms, UV spectra
  • Calculated peak results including retention times, area, and plates All details are stored in the chromatography data system. However, the information is distributed in several places:
  • Raw data file
  • Instrument settings in the configuration file or audit trail
  • Sample information in the database
  • Result information in the database or file

To describe a chromatography application consistently, all the information needs to be collected and synthesized in a format that is
easily accessible to the analyst.


Soil Analysis

Analyses of environmental matrices other than water are necessary to ensure clean air, contamination free soil, and proper disposal of hazardous wastes. Dionex leads the way in innovative solutions for the analysis of air, soil, and wastes. Key to good ion and liquid chromatography applications is sample preparation.

Dionex offers industry-leading technology with Accelerated Solvent Extraction (ASE®) for fast, accurate sample preparation of air filters, soils, solids, and wastes. Coupled with rapid solvent reduction systems, the often labor-intensive steps of sample preparation can be automated in your laboratory. Make certain you have the latest information about Dionex instrumentation, methods, and solutions for your environmental air, soil, and waste analyses.

Extraction of contaminants from solid matrices like soil, sediments, and sludge can be a difficult process, often taking up to eight hours or more. Extractions that normally take hours can be performed in minutes using Accelerated Solvent Extraction (ASE) systems with pH-hardened pathways using Dionium™ components. Compared to techniques like Soxhlet and sonication, ASE generates results in a fraction of the time.

The steps involved in sample preparation can now be automated with ASE flow-through technology. Filtration and cleanup of solid samples can be achieved as part of the solvent extraction process in a single step. ASE offers a lower cost per sample than other techniques, reducing solvent consumption by up to 90%.

ASE is a patented technique for the extraction of solid and semisolid sample matrices using common solvents at elevated temperatures and pressures. ASE systems are available in both the entry-level ASE 150 system, and fully automated ASE 350.
For extraction of environmental samples, ASE has been proven to be applicable to a wide variety of contaminants:

  • Pesticides and herbicides
  • PAHs and semivolatiles
  • PCBs
  • Dioxins and furans
  • TPH (DRO)
  • Explosives
  • Air sampling cartridges (XAD and PUFs)
  • Brominated flame retardants

Air Analysis

As a leader in air sampling, URG has a family of products for air sampling including denuders and particle analyzers. As the ion chromatography leader and developers of Reagent-Free™ IC systems, Dionex provides the ultimate in air analysis capabilities. URG and Dionex have teamed up to provide a complete solution for air monitoring. The result is a turnkey system specific to your needs.


Measurement Capabilities

The 9000 Series Ambient Ion Monitors are available in four configurations for the online determination of air particulate matter (PM) below 2.5u’s.


  • The URG-9000A Ambient Ion Monitor (AIM) provides time-resolved direct measurements of anion particulate nitrate, sulfate, nitrite, phosphate, and chloride found in PM-2.5. nitrite and sulfate aerosols are produced as a result of the interaction of ammonia (NH3), NOx, SO2, and other gaseous constituents.
  • The URG-9000B Ambient Ion Monitor (AIM) has an additional Ion Detector to allow for time-resolved direct measurements of cation particulate ammonium, sodium, calcium, potassium, and magnesium in addition to the anion particulate.
  • The URG-9000C Ambient Ion Monitor (AIM) provides time-resolved direct measurements of anion gases hydrogen chloride, nitric acid, nitrous acid, and sulfur dioxide in addition to the anion particulate.
  • The URG-9000D Ambient Ion Monitor (AIM) provides time-resolved measurements of ammonia in addition to the anion gases, anion particulate, and cation particulate

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Water Analysis

Everyone in the global community is impacted by the quality of water resources. The water we drink must be free from harmful chemicals to ensure good health. The purity of ground and surface waters in our environment is critical to ensuring sustainable use. The water discharged by municipal waste water treatment plants and industrial facilities must be monitored to ensure strict compliance with environmental guidelines. Process waters must be kept clean from contaminants to ensure product quality and acceptable exposure levels.


Dionex is committed to enhancing the quality of our global water resources. As innovation leaders in ion and liquid chromatography, our analytical instruments are used by government and industry to provide solutions for environmental water testing for a wide range of regulated and emerging inorganic elements and organic compounds. For an overview of our environmental water analysis capabilities, please download our brochure Water Analysis for a Global Market.

As pioneers of suppression technology, Dionex started a revolution in ion chromatography (IC) that increased the sensitivity and accuracy of ion determination. As constant innovators, we developed Reagent-Free™ IC (RFIC™) systems that set a new benchmark for ion analysis. Today, RFIC systems with Eluent Generation and Eluent Regeneration provide the ultimate in sensitivity and ease of use.

We also have a full HPLC product line for the analysis of organic contaminants, from nano- to preparative-scale separation capabilities, including UHPLC.

In fact, we are the only separations science company that provides instrumentation, columns, and applications perfectly suited for both inorganic and organic contaminants.

  • Ground and Surface Water
  • Drinking and Bottled Water
  • Wastewater
  • Process Waters
  • Water Analysis Regulations
  • Fast Water Analysis

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